Heterocyclic lipids conjugated to mRNA vaccines increase anti-tumor efficacy

October 01, 2019
Emerging Ecosystems in Agrifood and Health More...
by Joshua Haslun
Very important

A team at the Koch Institute for Integrative Cancer Research and the Massachusetts Institute of Technology identified lipid nanoparticles that not only aid in the delivery of scalable RNA vaccines but also act as adjuvants, boosting a vaccine's effectiveness. This is a solution to an ongoing issue for RNA vaccines, developing sufficient immunogenicity. While the initial research targets anti-tumor applications, there are numerous adjacent applications for the lipid nanoparticles across human and animal health. RNA vaccines are available for the livestock industry, but as herd health and management drives industry innovation and diseases impair production, clients should consider lipid nanoparticles for improved mRNA vaccine efficacy.

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