Company Profile | September 29, 2021
Genetically modifies E. coli to convert gas feedstocks like CO2 and methane into higher‑value chemicals Products of interest include 3‑hydroxypropionate (3‑HP) and its derivatives as well as novel polyhydroxyalkanoates (PHAs); developing other products with partners but would not disclose ... Not part of subscription
Company Profile | February 16, 2021
Claims efficient production of cost‑competitive "green" products from nonfood biomass; addresses some key weaknesses of conventional bioprocesses by offering resistance to inhibitors and making use of C5 as well as C6 sugars Focuses on five main products: L‑alanine (commercialized), L‑... Not part of subscription
News Commentary | September 16, 2021
The MIT and Montana State University research team included Feng Zhang, the noted CRISPR patent holder. The work outlines a new system of RNA‑guided endonucleases that the team calls Obligate Mobile Element Guided Activity (OMEGA) and includes more than 1 million suspected loci for one of OMEGA, ... Not part of subscription
by Thomas Hayes
Tufts developed a very similar process to the one from the University of Illinois, but it utilizes galactose as a feedstock instead of lactose. Tufts claims a yield up to 85%, whereas the University of Illinois claimed up to 90%. Bonumose still offers a more potent pathway to cost-effective tagatose (and rare sugars in general), but the company has been quiet since 2017. Since then, it did receive strategic investment from Bangchak Corporation in 2018, but there is little evidence that the company will succeed in scaling up within the next one or two years. Rather than waiting it out, clients should seed research on fermentation approaches from the likes of Tufts and the University of Illinois, as these are promising routes to rare sugars.
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